Fear conditioning and the basolateral amygdala
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چکیده
منابع مشابه
Long-Term Memory for Pavlovian Fear Conditioning Requires Dopamine in the Nucleus Accumbens and Basolateral Amygdala
The neurotransmitter dopamine (DA) is essential for learning in a pavlovian fear conditioning paradigm known as fear-potentiated startle (FPS). Mice lacking the ability to synthesize DA fail to learn the association between the conditioned stimulus and the fear-inducing footshock. Previously, we demonstrated that restoration of DA synthesis to neurons of the ventral tegmental area (VTA) was suf...
متن کاملOvertraining does not mitigate contextual fear conditioning deficits produced by neurotoxic lesions of the basolateral amygdala.
The influence of overtraining on the magnitude of fear-conditioning deficits produced by neurotoxic lesions of the basolateral amygdala (BLA) was examined. Either 1 d before or 1 week after the administration of neurotoxic BLA lesions, rats received either 1 or 25 conditioning trials consisting of the delivery of unsignaled foot shock in a novel observation chamber; freezing served as the measu...
متن کاملWhy We Think Plasticity Underlying Pavlovian Fear Conditioning Occurs in the Basolateral Amygdala
Lesions of the amygdala produce a pronounced and Michael S. Fanselow*‡ and Joseph E. LeDoux† *Department of Psychology and Brain Research Institute University of California, Los Angeles Los Angeles, California 90095 †Center for Neural Science often complete loss of a large number of Pavlovian conNew York University ditional fear responses, including freezing, potentiated New York, New York 1000...
متن کاملWhy We Think Plasticity Underlying Viewpoint Pavlovian Fear Conditioning Occurs in the Basolateral Amygdala
Lesions of the amygdala produce a pronounced and Michael S. Fanselow*‡ and Joseph E. LeDoux† *Department of Psychology and Brain Research Institute University of California, Los Angeles Los Angeles, California 90095 †Center for Neural Science often complete loss of a large number of Pavlovian conNew York University ditional fear responses, including freezing, potentiated New York, New York 1000...
متن کاملReduced fear conditioning after viral vector mediated neuropeptide Y administration into the basolateral amygdala
Background Neuropeptide Y (NPY) is a 36-amino-acid peptide that is abundantly expressed in the central nervous system. It is involved in various physiological and pathophysiological processes, including energy homeostasis, pain and epilepsy, but also in anxiety and depression. Consistent findings have demonstrated an anxiolytic effect of NPY. The presence of different NPY receptors in the amygd...
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ژورنال
عنوان ژورنال: F1000Research
سال: 2020
ISSN: 2046-1402
DOI: 10.12688/f1000research.21201.1